Kinetics of TNF-alpha and IFN-gamma mRNA expression in islets and spleen of NOD mice
Insulin-dependent diabetes mellitus is caused by autoimmune destruction of pancreatic ß cells. Non-obese diabetic (NOD) mice spontaneously develop diabetes similar to the human disease. Cytokines produced by islet-infiltrating mononuclear cells may be directly cytotoxic and can be involved in islet...
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| Huvudupphov: | , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
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Associação Brasileira de Divulgação Científica
2002-11-01
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| Serie: | Brazilian Journal of Medical and Biological Research |
| Ämnen: | |
| Länkar: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002001100013 |
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