Using plasma viral load to guide antiretroviral therapy initiation to prevent HIV-1 transmission.

Current WHO guidelines recommend antiretroviral therapy (ART) initiation at CD4 counts ≤350 cells/µL. Increasing this threshold has been proposed, with a primary goal of reducing HIV-1 infectiousness. Because the quantity of HIV-1 in plasma is the primary predictor of HIV-1 transmission, considerati...

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Hlavní autoři:	Pamela M Murnane, James P Hughes, Connie Celum, Jairam R Lingappa, Nelly Mugo, Carey Farquhar, James Kiarie, Anna Wald, Jared M Baeten, Partners in Prevention HSV/HIV Transmission Study Team
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2012-01-01
Edice:	PLoS ONE
On-line přístup:	http://europepmc.org/articles/PMC3511400?pdf=render
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