Tissue- and tumor-type-specific expression of internal-promoter-driven YEATS-domain-devoid isoforms of MLLT1 and MLLT3

Abstract As integral parts of the transcription super elongation complex, the ENL and AF9 proteins are two master regulators of gene expression involved in the development and homeostasis of various tissues. They are encoded by MLLT1 and MLLT3, two genes that frequently undergo oncogenic mutations o...

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Bibliografiske detaljer

Principais autores:	Sandra Dailhau, Ahmed Zamani, Romain Pfeifer, Chloé Bessière, Thérèse Commes, Olivera Casar-Borota, Christian Touriol, Fabienne Meggetto, Marina Bousquet, Nicolas Gilbert, Stéphane Pyronnet
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMC 2026-05-01
Serier:	Biomarker Research
Fag:	MLLT1 MLLT3 ENL AF9 Hematopoiesis Acute myeloid leukemia
Online adgang:	https://doi.org/10.1186/s40364-026-00928-w
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