Exosomal FASN Impairs Diabetic Wound Angiogenesis Via Mitochondrial Dysfunction

Aim or purpose: To delineate how Fasn-enriched circulating exosomes in diabetes disrupt endothelial lipid homeostasis and angiogenesis via mitochondrial regulation in the wound healing process. Materials and methods: Serum exosomes from type 2 diabetic mice and controls (n=10) were characterized by...

Full description

Saved in:
Bibliographic Details
Main Authors: Jiani Liu, Yimin Zhao, Geng Dou
Format: Artigo
Language:Inglês
Published: Elsevier 2025-10-01
Series:International Dental Journal
Subjects:
diabetic skin healing
angiogenesis
lipid metabolism
Fatty acid synthase
mitochondrial dysfunction
Online Access:http://www.sciencedirect.com/science/article/pii/S0020653925033398
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items