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Adaptive evolution of HIV at HLA epitopes is associated with ethnicity in Canada.

Host immune selection pressure influences the development of mutations that allow for HIV escape. Mutation patterns induced in HIV by the human leukocyte antigen (HLA) are HLA-allele specific. As ethnic groups have distinct and characteristic HLA allele frequencies, we can expect divergent viral evo...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Manon Ragonnet-Cronin, Stéphane Aris-Brosou, Isabelle Joanisse, Harriet Merks, Dominic Vallee, Kyna Caminiti, Paul Sandstrom, James Brooks
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science (PLoS) 2012-01-01
Sarja:PLoS ONE
Linkit:http://europepmc.org/articles/PMC3365047?pdf=render
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