Artesunate-loaded thermosensitive chitosan hydrogel promotes osteogenesis of maxillary tooth extraction through regulating T lymphocytes in type 2 diabetic rats

Abstract Background Type 2 diabetes mellitus (T2DM) causes severe bone loss after tooth extraction as a hyperglycemic environment causes aberrant bone homeostasis. Artesunate (ART) is known to possess anti-inflammation and osteogenic properties. However, its osteogenesis property in alveolar bone re...

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Detalles Bibliográficos

Principais autores:	Jinghong Luo, Chen Liang, Kun Chen, Kai Zeng, Rui Bai, Chan Tang, Jiaquan Li, Xiaolin Nong
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2024-03-01
Series:	BMC Oral Health
Assuntos:	Artesunate Hydrogel Type 2 diabetes mellitus Osteogenesis Mitogen-activated protein kinase kinases
Acceso en liña:	https://doi.org/10.1186/s12903-024-04127-7
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