Correlation of <i>TP53</i> Genetic Alterations with p53 Immunohistochemical Expression and Their Prognostic Significance in DLBCL

<i>TP53</i> genetic alterations represent a critical molecular feature in diffuse large B-cell lymphoma (DLBCL), with well-established associations with aggressive disease behavior and therapeutic resistance. However, significant controversy persists regarding the clinical utility of p53...

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Hlavní autoři: Chen Chen, Zijuan Hu, Min Ren, Longlong Bao, Ran Wei, Tian Tian, Xiaoli Zhu, Qianming Bai, Baohua Yu, Xiaoqiu Li, Xiaoyan Zhou
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2025-08-01
Edice:Current Oncology
Témata:
diffuse large B-cell lymphoma
<i>TP53</i> mutations
next-generation sequencing
copy number variation
p53 immunohistochemistry
prognostic markers
On-line přístup:https://www.mdpi.com/1718-7729/32/9/488
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