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PTTG1 regulates the TGF-β/Smad pathway to promote the growth and metastasis of gastric cancer cells

Abstract Background Pituitary tumor-transforming gene 1 (PTTG1) has been implicated in multiple malignancies; however, its precise role and regulatory mechanism in gastric cancer remain unclear. This study aimed to determine how PTTG1 regulates cell proliferation, migration, and epithelial–mesenchym...

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Autors principals: Dong Wang, Hui Geng, Ziwei Xia, Chenjie Qiu
Format: Artigo
Idioma:Inglês
Publicat: BMC 2026-02-01
Col·lecció:Hereditas
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Accés en línia:https://doi.org/10.1186/s41065-026-00647-0
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