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A case of intraplacental gestational choriocarcinoma; characterised by the methylation pattern of the early placenta and an absence of driver mutations

Abstract Background Gestational choriocarcinoma is a rare malignancy believed to arise from the trophoblast cells of the placenta. Despite the frequently aggressive clinical nature, choriocarcinoma has been routinely curable with cytotoxic chemotherapy for over 50 years. To date little is known rega...

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Principais autores: Philip Savage, David Monk, Jose R. Hernandez Mora, Nick van der Westhuizen, Jennifer Rauw, Anna Tinker, Wendy Robinson, Qianqian Song, Michael J. Seckl, Rosemary A. Fisher
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2019-07-01
Serier:BMC Cancer
Fag:
Oncogenesis
Trophoblast
Placenta
Choriocarcinoma
Methylation
Epigenetics
Online adgang:http://link.springer.com/article/10.1186/s12885-019-5906-8
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