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Current strategies and novel immunotherapeutic approaches for overcoming immune resistance in glioblastoma

Abstract Glioblastoma (GBM) is the most aggressive primary malignant brain tumor, characterized by rapid proliferation, extensive invasion, and significant genetic heterogeneity. Despite the availability of standard treatments such as surgical resection, radiotherapy, and chemotherapy, the prognosis...

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Principais autores: Mehrdad Nourizadeh, Saeid Mohammadzadeh Mounesyar, Mahdi Salimi Movahhed, Kasra Alipour, Rozhan Zekavatbakhsh, Mobina Hoseinzadeh, Shaghayegh Davari, Mehdi Amirhooshangi, Hadi Amirhoushangi, Sina Hamzehzadeh
Format: Artigo
Sprog:Inglês
Udgivet: Springer 2025-10-01
Serier:Discover Oncology
Fag:
Glioblastoma
Immunotherapy
Gene editing
Nanoparticles
CAR-T
Exosomes
Online adgang:https://doi.org/10.1007/s12672-025-03807-2
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