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Noncrystalline uric acid inhibits proteoglycan and glycosaminoglycan synthesis in distal tubular epithelial cells (MDCK)

Hyperuricemia is associated with renal stones, not only consisting of uric acid (UrAc) but also of calcium oxalate (CaOx). Glycosaminoglycans (GAGs) are well-known inhibitors of growth and aggregation of CaOx crystals. We analyzed the effect of noncrystalline UrAc on GAG synthesis in tubular distal...

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Principais autores: F.T. Borges, M.A. Dalboni, Y.M. Michelacci, N. Schor
Formato: Artigo
Idioma:Inglês
Publicado: Associação Brasileira de Divulgação Científica 2010-10-01
Series:Brazilian Journal of Medical and Biological Research
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Acceso en liña:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010001000006
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