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Rpl3l gene deletion in mice reduces heart weight over time

Introduction: The ribosomal protein L3-like (RPL3L) is a heart and skeletal muscle-specific ribosomal protein and paralogue of the more ubiquitously expressed RPL3 protein. Mutations in the human RPL3L gene are linked to childhood cardiomyopathy and age-related atrial fibrillation, yet the function...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Kelly M. Grimes, Vikram Prasad, Jiuzhou Huo, Yasuhide Kuwabara, Davy Vanhoutte, Tanya A. Baldwin, Stephanie L. K. Bowers, Anne Katrine Z. Johansen, Michelle A. Sargent, Suh-Chin J. Lin, Jeffery D. Molkentin
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2023-01-01
Rangatū:Frontiers in Physiology
Ngā marau:
heart
ribosome
translation
hypertrophy
gene expression
Urunga tuihono:https://www.frontiersin.org/articles/10.3389/fphys.2023.1054169/full
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