Erythropoietin Gene Therapy Delays Retinal Degeneration Resulting from Oxidative Stress in the Retinal Pigment Epithelium

Erythropoietin (EPO) plays an important role in erythropoiesis by its action in blocking apoptosis of progenitor cells and protects both photoreceptors and retinal ganglion cells from induced or inherited degeneration. A modified form of EPO, EPO-R76E has attenuated erythropoietic activity but is ef...

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Hlavní autoři:	Manas R. Biswal, Zhaoyao Wang, Ryan J. Paulson, Rukshana R. Uddin, Yao Tong, Ping Zhu, Hong Li, Alfred S. Lewin
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2021-05-01
Edice:	Antioxidants
Témata:	age related macular degeneration oxidative stress MnSOD RPE retinal degeneration erythropoietin
On-line přístup:	https://www.mdpi.com/2076-3921/10/6/842
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