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MicroRNA-128-3p is a novel oncomiR targeting PHF6 in T-cell acute lymphoblastic leukemia

T-cell acute lymphoblastic leukemia arises from the leukemic transformation of developing thymocytes and results from cooperative genetic lesions. Inactivation of the PHF6 gene is frequently observed in T-cell acute lymphoblastic leukemia, suggesting an important tumor suppressive role for PHF6 in t...

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Auteurs principaux: Evelien Mets, Gert Van Peer, Joni Van der Meulen, Michael Boice, Tom Taghon, Steven Goossens, Pieter Mestdagh, Yves Benoit, Barbara De Moerloose, Nadine Van Roy, Bruce Poppe, Jo Vandesompele, Hans-Guido Wendel, Pieter Van Vlierberghe, Frank Speleman, Pieter Rondou
Format: Artigo
Langue:Inglês
Publié: Ferrata Storti Foundation 2014-08-01
Collection:Haematologica
Accès en ligne:https://haematologica.org/article/view/7112
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