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ERRγ-inducible FGF23 promotes alcoholic liver injury through enhancing CYP2E1 mediated hepatic oxidative stress

Fibroblast growth factor 23 (FGF23) is a member of endocrine FGF family, along with FGF15/19 and FGF21. Recent reports showed that under pathological conditions, liver produces FGF23, although the role of hepatic FGF23 remains nebulous. Here, we investigated the role of hepatic FGF23 in alcoholic li...

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Principais autores: Yoon Seok Jung, Kamalakannan Radhakrishnan, Seddik Hammad, Sebastian Müller, Johannes Müller, Jung-Ran Noh, Jina kim, In-Kyu Lee, Sung Jin Cho, Don-Kyu Kim, Yong-Hoon Kim, Chul-Ho Lee, Steven Dooley, Hueng-Sik Choi
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-05-01
Serier:Redox Biology
Fag:
ERRγ
Alcoholic liver disease
FGF23
CYP2E1
Oxidative stress
Online adgang:http://www.sciencedirect.com/science/article/pii/S2213231724000831
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