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A positive feedback loop between TAZ and miR-942-3p modulates proliferation, angiogenesis, epithelial-mesenchymal transition process, glycometabolism and ROS homeostasis in human bladder cancer

Abstract Background Transcriptional coactivator with PDZ-binding motif (TAZ) has been reported to be involved in tumor progression, angiogenesis, epithelial-mesenchymal transition (EMT), glycometabolic modulation and reactive oxygen species (ROS) buildup. Herein, the underlying molecular mechanisms...

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Главные авторы: Feifan Wang, Mengjing Fan, Xuejian Zhou, Yanlan Yu, Yueshu Cai, Hongshen Wu, Yan Zhang, Jiaxin Liu, Shihan Huang, Ning He, Zhenghui Hu, Guoqing Ding, Xiaodong Jin
Формат: Artigo
Язык:Inglês
Опубликовано: BMC 2021-01-01
Серии:Journal of Experimental & Clinical Cancer Research
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Online-ссылка:https://doi.org/10.1186/s13046-021-01846-5
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