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Effects of combined metformin and semaglutide therapy on body weight, metabolic parameters, and reproductive outcomes in overweight/obese women with polycystic ovary syndrome: a prospective, randomized, controlled, open-label clinical trial

Abstract Objective This study aimed to assess the effects of metformin (MET) monotherapy versus a combination of semaglutide and MET on weight, metabolism, reproductive function, and inflammatory markers in women with polycystic ovary syndrome (PCOS). Methods A total of 100 overweight or obese women...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Haiyan Chen, Xiaohui Lei, Zhuoran Yang, Yuxin Xu, Dongfang Liu, Cong Wang, Hu Du
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2025-07-01
Rangatū:Reproductive Biology and Endocrinology
Ngā marau:
Urunga tuihono:https://doi.org/10.1186/s12958-025-01447-3
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