Multifunctional astragalus polysaccharide composited microneedle promotes oral ulcers healing by inhibiting ferroptosis via Nrf2/HO-1/SLC7A11 axis

Oral ulcers, a prevalent mucosal disorder with high recurrence rates, remain challenging to treat due to the oral cavity's dynamic environment and the multifactorial nature of ulcer progression. Here, we report a multifunctional microneedle (MN) patch loaded with astragalus polysaccharide (APS-MN) t...

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Hlavní autoři:	Qiang Zhang, Tuo Wang, Junyu Ren, Yanru Guo, Ziyi Yin, Chenrui Zhang, Honglin Fan, Yinting Ren, Junlong Da, Narisu Hu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2025-06-01
Edice:	Materials Today Bio
Témata:	Oral ulcers Astragalus polysaccharide Microneedle ROS Ferroptosis
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2590006425004338
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