Timing of Interleukin-4 Stimulation of Macrophages Determines Their Anti-Microbial Activity during Infection with <i>Salmonella enterica</i> Serovar Typhimurium

Priming of macrophages with interferon-gamma (IFNγ) or interleukin-4 (IL-4) leads to polarisation into pro-inflammatory or anti-inflammatory subtypes, which produce key enzymes such as inducible nitric oxide synthase (iNOS) and arginase 1 (ARG1), respectively, and in this way determine host response...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Natascha Brigo, Emely Neumaier, Christa Pfeifhofer-Obermair, Philipp Grubwieser, Sabine Engl, Sylvia Berger, Markus Seifert, Vera Reinstadler, Herbert Oberacher, Günter Weiss
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2023-04-01
Schriftenreihe:	Cells
Schlagworte:	interleukin-4 arginase 1 interferon-gamma inducible nitric oxide synthase <i>Salmonella enterica</i> serovar Typhimurium macrophages
Online-Zugang:	https://www.mdpi.com/2073-4409/12/8/1164
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