S-adenosylhomocysteine hydrolase over-expression does not alter S-adenosylmethionine or S-adenosylhomocysteine levels in CBS deficient mice

Elevated plasma total homocysteine (tHcy) is associated with a number of human diseases including coronary artery disease, stroke, osteoporosis and dementia. It is highly correlated with intracellular S-adenosylhomocysteine (SAH). Since SAH is a strong inhibitor of methyl-transfer reactions involvin...

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Váldodahkkit:	Hyung-Ok Lee, Liqun Wang, Yin-Ming Kuo, Andrew J. Andrews, Sapna Gupta, Warren D. Kruger
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Elsevier 2018-06-01
Ráidu:	Molecular Genetics and Metabolism Reports
Liŋkkat:	http://www.sciencedirect.com/science/article/pii/S2214426918300028
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