Exploring the Gating Mechanism of the Human Copper Transporter, hCtr1, Using EPR Spectroscopy
Ctr1 is a membrane-spanning homotrimer that facilitates copper uptake in eukaryotic cells with high affinity. While structural details of the transmembrane domain of human Ctr1 have been elucidated using X-ray crystallography and cryo-EM, the transfer mechanisms of copper and the conformational chan...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI AG
2025-01-01
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| coleção: | Biomolecules |
| Assuntos: | |
| Acesso em linha: | https://www.mdpi.com/2218-273X/15/1/127 |
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