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Perioperative Management of Biologic and Targeted Synthetic DMARDs in Orthopedic Surgery: Balancing Infection Risk and Disease Control

The perioperative management of biologic and immunomodulatory therapies in patients undergoing orthopedic surgery poses a clinical challenge, primarily due to the increased risk of postoperative infections. Biologic agents, particularly TNF inhibitors and interleukin-targeting drugs, may impair host...

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Principais autores: Francesco Mancuso, Jacopo Angelini, Alen Zabotti, Francesco Russiani, Massimo Baraldo, Luca Quartuccio, Hemant Pandit, Paolo Di Benedetto, Araldo Causero
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2026-02-01
coleção:Microorganisms
Assuntos:
DMARDs
orthopedic infections
immunomodulatory therapies
chronic inflammatory arthritis
Clinical Pharmacology
Acesso em linha:https://www.mdpi.com/2076-2607/14/2/398
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