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Acute LPS exposure enhances susceptibility to peripheral prion infection

Abstract After peripheral infections, the initial accumulation of prions within secondary lymphoid tissues is essential for the transmission of disease to the brain. Macrophages are considered to sequester or destroy prions, but little was known of their impact on disease susceptibility after a peri...

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Detalhes bibliográficos
Principais autores: Reiss Pal, Charlotte M. Thomas, Khalid Salamat, Stephen J. Jenkins, Barry M. Bradford, Neil A. Mabbott
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2025-03-01
coleção:Scientific Reports
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Acesso em linha:https://doi.org/10.1038/s41598-025-94003-3
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