Aberrant APOBEC3C expression induces characteristic genomic instability in pancreatic ductal adenocarcinoma

Abstract Pancreatic ductal adenocarcinoma (PDAC) is a well-known lethal and heterogeneous disease. Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like (APOBEC) is an important mutagenic driver that has seldom been investigated in PDAC. Therefore, this study investigated the significance...

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Detalhes bibliográficos

Principais autores:	Yunzhen Qian, Yitao Gong, Xuan Zou, Yu Liu, Yusheng Chen, Ruijie Wang, Zhengjie Dai, Yesiboli Tasiheng, Xuan Lin, Xu Wang, Guopei Luo, Xianjun Yu, He Cheng, Chen Liu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2022-06-01
coleção:	Oncogenesis
Acesso em linha:	https://doi.org/10.1038/s41389-022-00411-9
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