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RNA binding of Hfq monomers promotes RelA-mediated hexamerization in a limiting Hfq environment

RelA stimulates RyhB small RNA–target mRNA interaction by promoting assembly of Hfq monomers into hexamers. Here the authors show that RelA-mediated Hfq hexamerization requires an initial binding of RNA to Hfq monomers.

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Auteurs principaux: Pallabi Basu, Maya Elgrably-Weiss, Fouad Hassouna, Manoj Kumar, Reuven Wiener, Shoshy Altuvia
Format: Artigo
Langue:Inglês
Publié: Nature Portfolio 2021-04-01
Collection:Nature Communications
Accès en ligne:https://doi.org/10.1038/s41467-021-22553-x
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