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A Software Architecture to Mimic a Ventricular Tachycardia in Intact Murine Hearts by Means of an All-Optical Platform

Optogenetics is an emerging method that uses light to manipulate electrical activity in excitable cells exploiting the interaction between light and light-sensitive depolarizing ion channels, such as channelrhodopsin-2 (ChR2). Initially used in the neuroscience, it has been adopted in cardiac resear...

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Principais autores: Francesco Giardini, Valentina Biasci, Marina Scardigli, Francesco S. Pavone, Gil Bub, Leonardo Sacconi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-01-01
coleção:Methods and Protocols
Assuntos:
optical mapping
voltage imaging
voltage sensitive dye
optical manipulation
optogenetics
channelrhodopsin-2
cardiac electrophysiology
LabVIEW
closed-loop
real-time analysis
Acesso em linha:http://www.mdpi.com/2409-9279/2/1/7
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