How do we choose the best donor for T-cell-replete, HLA-haploidentical transplantation?

Abstract In haploidentical stem cell transplantations (haplo-SCT), nearly all patients have more than one donor. A key issue in the haplo-SCT setting is the search for the best donor, because donor selection can significantly impact the incidences of acute and chronic graft-versus-host disease, tran...

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Principais autores:	Ying-Jun Chang, Leo Luznik, Ephraim J. Fuchs, Xiao-Jun Huang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2016-04-01
coleção:	Journal of Hematology & Oncology
Assuntos:	Unmanipulated haploidentical stem cell transplantation Donor Donor-specific anti-human leukocyte antigen antibody Natural killer alloreactivity Age Non-inherited maternal antigen mismatch
Acesso em linha:	http://link.springer.com/article/10.1186/s13045-016-0265-2
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