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Camalexin-Induced Apoptosis in Prostate Cancer Cells Involves Alterations of Expression and Activity of Lysosomal Protease Cathepsin D

Camalexin, the phytoalexin produced in the model plant Arabidopsis thaliana, possesses antiproliferative and cancer chemopreventive effects. We have demonstrated that the cytostatic/cytotoxic effects of camalexin on several prostate cancer (PCa) cells are due to oxidative stress. Lysosomes are vulne...

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Autors principals: Basil Smith, Diandra Randle, Roman Mezencev, LeeShawn Thomas, Cimona Hinton, Valerie Odero-Marah
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2014-04-01
Col·lecció:Molecules
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Accés en línia:http://www.mdpi.com/1420-3049/19/4/3988
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