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Mimicking 3D bone microenvironment using a hybrid hydrogel-nanocomposite scaffold and human adipose-derived stem cells for bone differentiation and vascularization

Bioengineered bone tissues could bypass limitations of traditional reconstructive methods such as bone grafts or foreign-body implants, but to date this approach has been limited by immaturity of engineered bones and vascularization. Pediatric human adipose-derived stem cells (hADSCs) can be derived...

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Principais autores: Amel Ibrahim, Oliver FW Gardner, Naira Rodriguez-Florez, John C Hutchinson, Alexander Seifalian, Daniel Thomas-Vazque, Neil J Sebire, David Dunaway, Neil W Bulstrode, Patrizia Ferretti
Formato: Artigo
Idioma:Inglês
Publicado em: ELS Publishing (ELSP) 2024-04-01
coleção:Biofunctional Materials
Assuntos:
adipose derived stem cells
biomaterial
bone
human
fibrin gel
micro-niche
tissue engineering
vascularization
Acesso em linha:https://elsp-homepage.oss-cn-hongkong.aliyuncs.compaper/journal/open/BM/2024/bm20240002.pdf
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