Computer-Aided Design of Peptidomimetic Inhibitors of Falcipain-3: QSAR and Pharmacophore Models

In this work, antiparasitic peptidomimetics inhibitors (PEP) of falcipain-3 (FP3) of <i>Plasmodium falciparum</i> (<i>Pf</i>) are proposed using structure-based and computer-aided molecular design. Beginning with the crystal structure of <i>Pf</i>FP3-K11017 complex (PDB ID: 3BWK), three-dimensional...

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Egile Nagusiak:	Boris D. Bekono, Akori E. Esmel, Brice Dali, Fidele Ntie-Kang, Melalie Keita, Luc C. O. Owono, Eugene Megnassan
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	MDPI AG 2021-09-01
Saila:	Scientia Pharmaceutica
Gaiak:	drug design falcipain malaria peptidomimetics <i>Plasmodium falciparum</i> virtual screening
Sarrera elektronikoa:	https://www.mdpi.com/2218-0532/89/4/44
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