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Sonic hedgehog is Essential for Proximal-Distal Outgrowth of the Limb Bud in Salamanders

The developing forelimb has been a foundational model to understand how specified progenitor cells integrate genetic information to produce the tetrapod limb bauplan. Although the reigning hypothesis is that all tetrapods develop limbs in a similar manner, recent work suggests that urodeles have evo...

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Autors principals: Sruthi Purushothaman, Brianda B. Lopez Aviña, Ashley W. Seifert
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2022-04-01
Col·lecció:Frontiers in Cell and Developmental Biology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fcell.2022.797352/full
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