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Sotorasib in KRAS p.G12C-Mutated Pulmonary Sarcomatoid Carcinoma: Therapeutic Efficacy of a KRAS Inhibitor in Symptomatic Brain Metastases

Introduction: Pulmonary sarcomatoid carcinomas (PSCs) are a rare subgroup of non-small cell lung cancer (NSCLC). In contrast to other NSCLCs, PSCs have a poor prognosis due to limited efficacy of radiation and chemotherapy. Therefore, other therapeutic approaches are needed. KRAS mutations occur in...

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Bibliografiske detaljer
Principais autores: Jonas Frederik Schmidt, Dominik Entz, Frank Brasch, Martin Goerner
Format: Artigo
Sprog:Inglês
Udgivet: Karger Publishers 2024-09-01
Serier:Case Reports in Oncology
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Online adgang:https://beta.karger.com/Article/FullText/540675
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