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Effect of Autophagy Inhibitors on Radiosensitivity in DNA Repair-Proficient and -Deficient Glioma Cells

<i>Background and Objectives</i>: The development of radioresistance is a fundamental barrier to successful glioblastoma therapy. Autophagy is thought to play a role in facilitating the DNA repair of DNA damage foci in radiation-exposed tumor cells, thus, potentially contributing to their restoratio...

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Hoofdauteurs: Tareq Saleh, Homood M. As Sobeai, Ali Alhoshani, Khalid Alhazzani, Mashal M. Almutairi, Moureq Alotaibi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2022-07-01
Reeks:Medicina
Onderwerpen:
DNA damage
autophagy
senescence
glioblastoma
DNA-PKcs
radiation
Online toegang:https://www.mdpi.com/1648-9144/58/7/889
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