Mechanistic Insights into Regulation of JAK2 Tyrosine Kinase
JAK2 is a member of the Janus kinase (JAKs) family of non-receptor protein tyrosine kinases, which includes JAK1–3 and TYK2. JAKs serve as the cytoplasmic signaling components of cytokine receptors and are activated through cytokine-mediated trans-phosphorylation, which leads to receptor phosphoryla...
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| Format: | Artigo |
| Sprache: | Inglês |
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Frontiers Media S.A.
2018-01-01
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| Schriftenreihe: | Frontiers in Endocrinology |
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| Online-Zugang: | http://journal.frontiersin.org/article/10.3389/fendo.2017.00361/full |
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