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Biosynthetic polyphosphate enhances osteogenesis of human periodontal ligament stem cells and promotes periodontal bone regeneration in a murine periodontal bone defect model

IntroductionPeriodontal bone regeneration remains a significant challenge in clinical dentistry due to the complex structure of periodontal tissues and their limited intrinsic regenerative capacity. Innovative biomaterial-based strategies are therefore required. Polyphosphates (Poly(P)) have shown p...

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Hlavní autoři: Jiaqi Chen, Dongying Lei, Xinyi Liu, Zipeng Chen, Jiaying Li, Liang Huang, Huifen Liu, Xuebin Yang, Wei Wei, Sijing Xie
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2025-09-01
Edice:Frontiers in Bioengineering and Biotechnology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1672295/full
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