Selectivity in C-alkylation of dianions of protected 6-methyluridine
A regioselective synthesis of 6-ω-alkenyluridines 3, precursors of potent antiviral and antitumor cyclonucleosides 5, is described. While ω-alkenyl halides do not alkylate 6-lithiouridine, compounds 3 were prepared in a regioselective manner by sequential treatment of 6-methyluridine 2 with LTMP or...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Beilstein-Institut
2011-09-01
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| Reeks: | Beilstein Journal of Organic Chemistry |
| Onderwerpen: | |
| Online toegang: | https://doi.org/10.3762/bjoc.7.143 |
| Tags: |
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