Comparison of the efficacy and safety of tacrolimus monotherapy and cyclophosphamide combined with glucocorticoid in the treatment of adult primary membranous nephropathy: protocol of a multicenter, randomized, controlled, open study

Abstract Background Idiopathic membranous nephropathy (IMN) remains the leading cause of adult nephrotic syndrome. Immunosuppressive therapy with cyclophosphamide (CTX) is often successful in reducing proteinuria, but its use is associated with severe side effects. Tacrolimus (TAC) is effective in a...

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Detalhes bibliográficos

Principais autores:	Shasha Chen, Song Ren, Amanda Y. Wang, Hieu Tran, Zheng Li, Xiaoyun Cheng, Manli Liu, Guisen Li, Li Wang, Daqing Hong
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2020-02-01
coleção:	Trials
Assuntos:	Tacrolimus, Cyclophosphamide, Glucocorticoid, Membranous nephropathy, Randomized controlled trial
Acesso em linha:	http://link.springer.com/article/10.1186/s13063-020-4144-3
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