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Sensitive assessment of the virologic outcomes of stopping and restarting non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy.

<h4>Background</h4>Non-nucleoside reverse transcriptase inhibitor (NNRTI)-resistant mutants have been shown to emerge after interruption of suppressive NNRTI-based antiretroviral therapy (ART) using routine testing. The aim of this study was to quantify the risk of resistance by sensitive testing an...

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Hlavní autoři: Anna Maria Geretti, Zoe Fox, Jeffrey A Johnson, Clare Booth, Jonathan Lipscomb, Lieven J Stuyver, Gilda Tachedjian, John Baxter, Giota Touloumi, Clara Lehmann, Andrew Owen, Andrew Phillips, INSIGHT Strategies for Management of Antiretroviral Therapy (SMART) Study Group
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2013-01-01
Edice:PLoS ONE
On-line přístup:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0069266&type=printable
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