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Androgen receptor activity is affected by both nuclear matrix localization and the phosphorylation status of the heterogeneous nuclear ribonucleoprotein K in anti-androgen-treated LNCaP cells.

The androgen receptor (AR) plays a central role in the development and progression of prostate cancer (PCa) and anti-androgen therapy is a standard treatment. Unfortunately, after a few years, the majority of patients progress, developing androgen-independent PCa. AR-driven gene transcription recrui...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Paola Barboro, Luana Borzì, Erica Repaci, Nicoletta Ferrari, Cecilia Balbi
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Public Library of Science (PLoS) 2013-01-01
Rangatū:PLoS ONE
Urunga tuihono:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24236111/pdf/?tool=EBI
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