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SNP allele frequency estimation in DNA pools and variance components analysis

The estimation of single nucleotide polymorphism (SNP) allele frequency in pooled DNA samples has been proposed as a cost-effective approach to whole genome association studies. However, the key issue is the allele frequency window in which a genotyping method operates and provides a statistically r...

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Autori principali: Kate Downes, Bryan J. Barratt, Pelin Akan, Sue J. Bumpstead, Stacey D. Taylor, David G. Clayton, Panos Deloukas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis Group 2004-05-01
Serie:BioTechniques
Accesso online:https://www.future-science.com/doi/10.2144/04365RR01
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