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Plasma pharmacokinetics of once-daily abacavir- and lamivudine-containing regimens and week 96 efficacy in HIV-infected Thai children

Background: Abacavir and lamivudine are approved for once-daily use in HIV-infected adults Limited pharmacokinetic (PK) data for abacavir and lamivudine in children are available. Methods: A crossover study to compare PK of once- versus twice-daily abacavir and lamivudine was conducted in virologica...

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Principais autores: Torsak Bunupuradah, Passorn Punyahotra, Tim R. Cressey, Amornrat Srimuan, Narukjaporn Thammajaruk, Jiratchaya Sophonphan, Chulalak Sriheara, David M. Burger, Thanyawee Puthanakit, Jintanat Ananworanich
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2015-07-01
Series:Journal of Virus Eradication
Assuntos:
abacavir
lamivudine
pharmacokinetics
once-daily
HIV-infected children
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2055664020305033
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