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Functional inactivation of the genome-wide association study obesity gene neuronal growth regulator 1 in mice causes a body mass phenotype.

To date, genome-wide association studies (GWAS) have identified at least 32 novel loci for obesity and body mass-related traits. However, the causal genetic variant and molecular mechanisms of specific susceptibility genes in relation to obesity are yet to be fully confirmed and characterised. Here,...

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Principais autores: Angela W S Lee, Heidi Hengstler, Kathrin Schwald, Mauricio Berriel-Diaz, Desirée Loreth, Matthias Kirsch, Oliver Kretz, Carola A Haas, Martin Hrabě de Angelis, Stephan Herzig, Thomas Brümmendorf, Martin Klingenspor, Fritz G Rathjen, Jan Rozman, George Nicholson, Roger D Cox, Michael K E Schäfer
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2012-01-01
Serier:PLoS ONE
Online adgang:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0041537&type=printable
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