Characterization and therapeutic potential of DepZ57, a stable depolymerase targeting hypervirulent K57 Klebsiella pneumoniae

ABSTRACT Klebsiella pneumoniae (K. pneumoniae) is recognized as a significant opportunistic pathogen capable of infecting both humans and animals. The emergence of multidrug-resistant strains presents a severe challenge to current antimicrobial therapies, necessitating the development of alternative...

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Autores principales:	Sixiang Xu, Mengmeng Su, Xiaoyue Li, Pei Li, Xiangkuan Zheng, Huanxin Fang, Yilin Fang, Peifan Liu, Long Chen, Zihao Pan, Zhongming Tan, Hong Du, Wei Zhang
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology 2026-07-01
Colección:	Applied and Environmental Microbiology
Materias:	Klebsiella pneumoniae bacteriophage depolymerase K57 serotype stability assessment In vivo efficacy
Acceso en línea:	https://journals.asm.org/doi/10.1128/aem.02535-25
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