HDAC4: an emerging target in diabetes mellitus and diabetic complications

Abstract Diabetes mellitus (DM) is a metabolic disease with complex pathogenic mechanisms. Histone deacetylase 4 (HDAC4) is a member of an important family of epigenetic modifications. An increasing amount of research indicates that HDAC4 may control DM by modulating the epigenetic and post-translat...

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Autors principals: Yiqi Lin, Yuetong Li, Caiying Ke, Ying Jin, Wanwen Lao, Yiling Wu, Yang Liu, Xinyi Kong, Jie Qiao, Aixia Zhai, Changlong Bi
Format: Artigo
Idioma:Inglês
Publicat: BMC 2025-05-01
Col·lecció:European Journal of Medical Research
Matèries:
Histone deacetylase 4
Diabetes mellitus
Epigenetic modifications
Signaling
HDAC4 inhibitors
Diabetic complications
Accés en línia:https://doi.org/10.1186/s40001-025-02697-y
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