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<i>BRCA1/2</i> Mutation Types Do Not Affect Prognosis in Ovarian Cancer Patients

Background: High grade serous ovarian carcinoma (HGSOC) is the most lethal type of epithelial ovarian cancer, with a prevalence of germline <i>BRCA1/2</i> mutations as high as 20%. Our objective is to determine whether the location of mutations in the different domains of the <i>BRCA1/2</i> genes af...

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Principais autores: Michalis Liontos, Eleni Zografos, Panagiotis Zoumpourlis, Angeliki Andrikopoulou, Anna Svarna, Oraianthi Fiste, Elena Kunadis, Alkistis Maria Papatheodoridi, Maria Kaparelou, Konstantinos Koutsoukos, Nikoloas Thomakos, Dimitrios Haidopoulos, Alexandros Rodolakis, Meletios-Athanasios Dimopoulos, Flora Zagouri
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-11-01
Serier:Current Oncology
Fag:
ovarian cancer
<i>BRCA</i>
germline mutations
survival
Online adgang:https://www.mdpi.com/1718-7729/28/6/377
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