Methylglyoxal Accumulation in Arterial Walls Causes Vascular Contractile Dysfunction in Spontaneously Hypertensive Rats

Methylglyoxal (MGO) is a metabolite of glucose and perhaps mediates diabetes-related macrovascular complications including hypertension. In the present study, we examined if MGO accumulation affects vascular reactivity of isolated mesenteric artery from spontaneously hypertensive rats (SHR). Five-we...

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Hlavní autoři:	Masashi Mukohda, Muneyoshi Okada, Yukio Hara, Hideyuki Yamawaki
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2012-01-01
Edice:	Journal of Pharmacological Sciences
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S134786131930461X
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