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Hetero-Diels–Alder and CuAAC Click Reactions for Fluorine-18 Labeling of Peptides: Automation and Comparative Study of the Two Methods

Radiolabeled peptides are valuable tools for diagnosis or therapies; they are often radiofluorinated using an indirect approach based on an F-18 prosthetic group. Herein, we are reporting our results on the F-18 radiolabeling of three peptides using two different methods based on click reactions. Th...

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Principais autores: Timothé Maujean, Sridévi M. Ramanoudjame, Stéphanie Riché, Clothilde Le Guen, Frédéric Boisson, Sylviane Muller, Dominique Bonnet, Mihaela Gulea, Patrice Marchand
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2024-07-01
Series:Molecules
Assuntos:
fluorine-18
peptide
cycloaddition
hetero-Diels–Alder
CuAAC
labeling
Acceso en liña:https://www.mdpi.com/1420-3049/29/13/3198
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