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Can white matter hyperintensities based Fazekas visual assessment scales inform about Alzheimer’s disease pathology in the population?

Abstract Background White matter hyperintensities (WMH) are considered hallmark features of cerebral small vessel disease and have recently been linked to Alzheimer’s disease (AD) pathology. Their distinct spatial distributions, namely periventricular versus deep WMH, may differ by underlying age-re...

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Asıl Yazarlar: Aishwarya Pradeep, Sheelakumari Raghavan, Scott A. Przybelski, Gregory M. Preboske, Christopher G. Schwarz, Val J. Lowe, David S. Knopman, Ronald C. Petersen, Clifford R. Jack, Jonathan Graff-Radford, Petrice M. Cogswell, Prashanthi Vemuri
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2024-07-01
Seri Bilgileri:Alzheimer’s Research & Therapy
Konular:
White matter hyperintensities
Alzheimer’s disease
Fazekas score
Periventricular white matter hyperintensity
Deep white matter hyperintensity
Online Erişim:https://doi.org/10.1186/s13195-024-01525-5
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