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Topical rosiglitazone is an effective anti-scarring agent in the cornea.

Corneal scarring remains a major cause of blindness world-wide, with limited treatment options, all of which have side-effects. Here, we tested the hypothesis that topical application of Rosiglitazone, a Thiazolidinedione and ligand of peroxisome proliferator activated receptor gamma (PPARγ), can ef...

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Autori principali: Krystel R Huxlin, Holly B Hindman, Kye-Im Jeon, Jens Bühren, Scott MacRae, Margaret DeMagistris, David Ciufo, Patricia J Sime, Richard P Phipps
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2013-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC3733781?pdf=render
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