Identification of differentially recognized T cell epitopes in the spectrum of tuberculosis infection

Abstract There is still incomplete knowledge of which Mycobacterium tuberculosis (Mtb) antigens can trigger distinct T cell responses at different stages of infection. Here, a proteome-wide screen of 20,610 Mtb-derived peptides in 21 patients mid-treatment for active tuberculosis (ATB) reveals IFNγ-...

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Detalhes bibliográficos

Principais autores:	Sudhasini Panda, Jeffrey Morgan, Catherine Cheng, Mayuko Saito, Robert H. Gilman, Nelly Ciobanu, Valeriu Crudu, Donald G. Catanzaro, Antonino Catanzaro, Timothy Rodwell, Judy S. B. Perera, Teshan Chathuranga, Bandu Gunasena, Aruna D. DeSilva, Bjoern Peters, Alessandro Sette, Cecilia S. Lindestam Arlehamn
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2024-01-01
coleção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-024-45058-9
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